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CompreChip

Perform migration assays and mechanobiological studies in a reproducible, miniaturized manner.

CompreVie - The product
So were we.
This is why we developed: the CompreChip
Comprevie - chip
© Farnaz Foroozesh

Features

• Miniaturized - analytical setup flexibility & low biomaterial costs
• Test eight samples per chip
• Compatible with several adhesive cell types & surface coating matrix
• Adjustable, automated mechanical stimulation in vitro
• Create circular reproducible cell-free areas
• Perform repeatable wounding of the same area without damaging the surface coating
• Reduction of injured cells along the edge of the cell-free area
• Removal of cell debris during perfusion
• Fit for sensor integration
• "Ready-to-start" system
As a lab-on-chip device, the CompreChip employs controlled pneumatic actuation of a flexible membrane to mechanically stimulate or wound tissues grown in the device's microchannels. Whether you want to study cell migration or study the effects of compressive stress on cell fate and morphology, this device can help you in your mission. Having the dimensions of a microscope slide, it is compatible with any image analysis system and can be used with several adherent cell types, thus facilitating a wide range of studies from cutaneous wound closure, to brain trauma, cancer cell studies, etc.
Time Lapse
CompreVie Element

Tissue regeneration studies made easy

Time-lapse images of the generated wounds at 0 , 4, 12, 16 and 20 hours after the automated CompreChip cell deptetion. (Scale bar=200 μm)

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